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January, 2016
New performance test available for Pigeons. Please see LDHA-1

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December, 2015
New test available for Horses. Please see Hoof Wall Separation Disease (HWSD)

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April 17, 2012
Animal Genetics publishes 3rd paper on Avian Borna Virus in Avian Diseases. Please contact us for a copy.

Performance Testing For Pigeons

Several genes have been linked to racing performance in pigeons. LDHA gene provides instructions for making a protein called lactate dehydrogenase-A, which is one piece of the lactate dehydrogenase enzyme. Two polymorphisms with in the dopamine receptor D4 (DRD4) have been linked to racing performance in (<400 km) races

 

 

 

Lactate is made by muscle fibers and is what causes the pain in skeletal muscle tissue when doing physical efforts, related to endurance, speed and power. Skeletal muscles are those muscles involved in movement. It's these muscles that are being trained when an athlete goes from arobic to anaerobic phase.

 

During high-intensity physical activity Skeletal muscles need increased amounts of energy. Anaerobic exercise occurs when the body's oxygen intake is not sufficient for the amount of energy required. To create additional energy, glucose stored in the body as glycogen gets broken down. During the breakdown of glycogen, the lactate dehydrogenase enzyme converts the molecule pyruvate into a similar molecule called lactate, which can be used by the body for energy.

 

The pain in these muscles during and after high physical exertion is in part a result of lactate buildup. The more an athlete reaches their maximum effort, the more lactate is made by the muscle fibers.

Test Results For LDHA1:

Research conducted by several groups has shown that mutations in Lactate dehydrogenase enzyme (LDHA) has been linked to overall performance in racing pigeons. These alleles (variations in a gene) have been labeled the names A (A) and B (G). Research suggests that genotype A was found significantly more often in top performances pigeons. There are 3 possible genotypes with these alleles, BB, AB and AA. The A allele is a rare variation, found in less then 12% of normal racing pigeons and less then 1% of pigeons had the statisticlly more favorable AA genotype. It is important to mention that some top racing pigeons are BB genotype meaning that the A allele is not absolutely necessary to be able to perform at a high level. This suggests that additional genes are involved in race performance including speed and distance.

Test Results For LDHA2:

Research conducted by several groups has shown that mutations in Lactate dehydrogenase enzyme (LDHA) has been linked to overall performance in racing pigeons.

Test Results For LDHA1:

    AA Homozygous The pigeon carries two copies of the A allele and is homozygous for A. The pigeon statistically is a better race performance bird. The pigeon will only pass on the A allele and not the B.
    AB Hetrozygous The pigeon carries both A and B alleles. The pigeon can pass on either the A or B allele 50% on the time.
    BB Homozygous The pigeon carries two copies B allele and is homozygous for B. The pigeon will only pass on the B allele and not the A.

    Submit a Sample for Testing:

    To submit a sample download a test submission form at our Downloads page.

  • Mail samples to:
  • Animal Genetics UK,
  • 1 Mount Charles Rd.
  • St. Austell Cornwall, PL25 3LB
  • ENGLAND