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New Canine Test
Animal Genetics offers new assay for Neuronal Ceroid Lipofuscinosis (NCL) in Golden Retrievers. Please visit NCLGR for more information.

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New Canine Test
Animal Genetics offers new assay for Susceptibility to Intervertebral Disc Disease (IVDD). Please visit IVDD for more information.

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New Canine Test
Animal Genetics offers new assay for Dermatomyositis in dogs. Please visit Dermatomyositis - DMS for more information.

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Canine Test
Animal Genetics will begin offering PRA-prcd testing. Please visit PRA-prcd For more information.

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Avian Test
Performance test available for Pigeons. Please see LDHA-1

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Avian Test
Test available for Horses. Please see Hoof Wall Separation Disease (HWSD)

Skeletal Dysplasia 2: dwarfism in the Labrador Retriever

Description:

Canine Skeletal Dysplasia 2 (SD2) is a mild form of disproportionate dwarfism found in Labrador Retrievers. It is generally characterized by one or more body parts being smaller in comparison to the overall size of the animal. Animals with SD2 develop legs that are shorter than unaffected legs, despite a normal body size. In most cases, the front legs are more severely affected than the hind legs. This causes an awkward stance and gait.

 

The SD2 variant is associated with disproportionate dwarfism in Labrador Retrievers and has displayed subtle effects. Unlike other forms of skeletal dysplasia, SD2 is not associated with any vision or hearing problems. Studies suggest that field or working lines of Labrador Retrievers are more likely to inherit the SD2 variant.

 

In most cases the affected males had shoulder heights of less than 55 cm and affected females had shoulder heights of less than 50 cm. The international breed standard is 56-57 cm for males and 54-56 cm for females.

 

Sample Type:

Animal Genetics accepts Buccal Swab, Blood, Dewclaw. Collection kits are available and can be ordered at test now.

Test Is Relevant to the Following Breeds:

Labrador Retriever

Results:

Animal Genetics offers DNA testing for Canine Cystinuria. The genetic test verifies the presence of the recessive CY gene and presents results as one of the following:

SD2/SD2 Affected The dog carries two copies of the mutant gene and is homozygous for SD2. The dog is affected by Skeletal Dysplasia 2.
SD2/n Carrier Both the normal and mutant copies of the gene detected. The dog is a carrier for Skeletal Dysplasia 2.
n/nClear Dog tested negative for the Skeletal Dysplasia 2 gene mutation, and will not pass on the defective gene to its offspring.